Agilent Blog

Steve Fillers

Recent Posts

Improved 384-Well Filter Microplates

Posted by Steve Fillers on May 5, 2017 1:30:08 PM

The Evolution of Continuous Improvement in Labware 

So goes the old adage: Why fix it if it ain’t broke? Definitely a worthy question, but just because something isn’t broken doesn’t mean improvement isn’t worth investigating. And sometimes, opportunities present themselves.

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Topics: Custom Microplates, 384-Well Filter Microplates, Improved 384-Well Filter Microplates

Maintaining and Improving the Quality of Microplates

Posted by Steve Fillers on Feb 8, 2017 10:06:51 AM

Interview with Lorraine Galica, Quality Manager

Lorraine Galica manages a large group of people and activities that contribute to the quality aspects of the microplate products at Agilent Technologies. A look from her perspective underscores the focus the Quality group has in exceeding customers’ expectations.

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Topics: Microplate, Microplates

Injection Molding Operations for Custom Microplates

Posted by Steve Fillers on Nov 22, 2016 11:59:56 AM

A Talk with Paul Duval, Process Technology Supervisor at Agilent

Paul Duval oversees molding operations at Agilent in Chicopee, MA. Pellets of polymer resins are transported into molding machines where they are melted and forced, with pressure at high velocity, into a microplate mold. The mold is pulled apart and the new plastic part is ejected out of the mold. New parts are subject to 100 percent inspection to ensure that Agilent’s product specifications are achieved.

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Topics: Microplates, Custom Microplates, Injection Molding Custom Microplates

Machining an Injection Mold to Produce Microplates

Posted by Steve Fillers on Apr 28, 2016 10:50:49 AM

An Interview with George Blais, Machining Supervisor

George Blais (pictured here) cuts metal into shapes that create molds to produce microplates. The metals usually arrive as large bars and plates that are progressively machined into pieces that can be assembled into a form. This form can then be mounted and connected to the flow of an injection molding machine. The machining phase has several stages required to optimize the specifications of the final microplate product.

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Topics: Microplate, Microplates, Injection Molds for Microplates

Designing an Injection Mold for Microplates

Posted by Steve Fillers on Mar 22, 2016 4:15:05 PM

Perspective of a Microplates Design Engineer

Injection molds create the unique characteristics of standard and custom microplates. Quite simply, a mold is a huge hunk of metal cut in half and milled out to flow molten polymers into the physical shape details of a microplate. The design phase directs the cutting of the steel to optimize the specifications of the final microplate product. But, as you might imagine, it’s not that simple.

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Topics: Microplates

Microplate Array Format Uses Are Limitless

Posted by Steve Fillers on Jan 19, 2016 3:12:00 PM

Amazing Applications for Microplates

Dr. Gyula Takatsy is credited for invention of the microplate in 1951 as a means to increase throughput and reduce the material requirements for running influenza detection assays. Since then, microplates have been considered a first step in automating various process. If you can get it to work in a test tube, chances are very good that you can increase productivity by employing microplate technology. Beyond just holding liquids, solids, and cells, some very clever applications* have been adapted to the microplate array format, as you'll discover in the examples below.

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Topics: Microplates, Microplate Array, Microplate Array Format

Optimize Pipette Operations with Reagent Reservoir Selection

Posted by Steve Fillers on Dec 7, 2015 11:33:00 AM

Specialized Microplate Reagent Reservoirs Simplify Small Volume Transfers

I am certain that many of you reading this blog have had occasion to employ a pipette tip box lid as a reagent reservoir. They are quick, easy and cheap! However, several serious limitations become immediately obvious—especially when automation equipment is involved in your process.

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Topics: Reagent Reservoirs, Pipettors

Is Filter Plate Drip Length Important?

Posted by Steve Fillers on Oct 1, 2015 4:48:28 PM

Choosing the Right Filter Plate Drip Length Does Matter

To answer this question—and to find which length is best suited for your needs—it’s important to understand the three general methods that are employed for filtration using microplates.

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Topics: Microplates

Using the Right Microplate—What If My Process Is Sterile?

Posted by Steve Fillers on Jul 17, 2015 5:45:00 PM

Sterilization Methods for Microplates

Typical molding temperatures for polypropylene microplates are 450°F or greater and most post-molding and packaging operations occur under ISO quality standards in certified clean rooms. Nevertheless, if you are doing everything known to man to support biological growth or replication in your experiments, you would want to start out with sterile materials.

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Topics: Microplates, Custom Microplate Specifications, Microplate Labware